Pituitary metastasis: is there still a place for neurosurgical treatment?

Fiche publication


Date publication

janvier 2016

Journal

Journal of neuro-oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PROUST François


Tous les auteurs :
Gilard V, Alexandru C, Proust F, Derrey S, Hannequin P, Langlois O

Résumé

Pituitary metastases are uncommon, ranging from 1 to 5 % of all metastases. Between 10 and 30 % of pituitary lesions are symptomatic responsible for diabetes insipidus, visual field defect or cranial nerve palsy. Primary sites are lung or breast in two-thirds of cases. There is no current reference concerning treatment of such lesions. Overall survival is poor and depends on primary site. Although the role of surgery is currently limited, discussion is warranted in several indications for diagnostic or symptomatic purposes. We report two cases of symptomatic pituitary metastases in a context of breast cancer and review the litterature concerning the role of surgery and other treatment modalities.

Mots clés

Pituitary gland- metastases, Surgical treatment

Référence

J Neurooncol. 2016 01;126(2):219-24