Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways.
Fiche publication
Date publication
novembre 2017
Journal
The British journal of dermatology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BENSUSSAN Armand
Tous les auteurs :
Michel L, Reygagne P, Benech P, Jean-Louis F, Scalvino S, Ly Ka So S, Hamidou Z, Bianovici S, Pouch J, Ducos B, Bonnet M, Bensussan A, Patatian A, Lati E, Wdzieczak-Bakala J, Choulot JC, Loing E, Hocquaux M
Lien Pubmed
Résumé
Male androgenetic alopecia (AGA) is the most common form of hair loss in men. It is characterized by a distinct pattern of progressive hair loss starting from the frontal area and the vertex of the scalp. Although several genetic risk loci have been identified, relevant genes for AGA remain to be defined.
Mots clés
25-Hydroxyvitamin D3 1-alpha-Hydroxylase, metabolism, Adult, Alopecia, genetics, Analysis of Variance, Bone Morphogenetic Proteins, genetics, Case-Control Studies, Catenins, genetics, DNA, Complementary, genetics, Down-Regulation, genetics, Gene Expression, genetics, Gene Expression Profiling, methods, Genetic Markers, Hair Follicle, metabolism, Humans, Male, Signal Transduction, genetics, Transforming Growth Factor beta, genetics, Up-Regulation, genetics, Vitamin D, genetics, Wnt Signaling Pathway, genetics
Référence
Br J Dermatol. 2017 11;177(5):1322-1336