Multimodal management of severe herpes simplex virus encephalitis: A case report and literature review.

Fiche publication


Date publication

juin 2018

Journal

Neuro-Chirurgie

Auteurs

Membres identifiés du Cancéropôle Est :
Dr CEBULA Hélène, Pr PROUST François


Tous les auteurs :
Todeschi J, Gubian A, Wirth T, Coca HA, Proust F, Cebula H

Résumé

Herpes simplex encephalitis (HSE) is the most frequent sporadic encephalitis in the world. In severe cases of HSE, the pathology usually progresses with an increase in intracranial pressure secondary to cerebral edema and/or hemorrhagic necrosis. Currently no high-power studies exist regarding the management of severe HSE and most of the papers reported in the literature are case reports. Decompressive craniectomy, effective in some cases of pharmaco-resistant intracranial hypertension (ICH) resulting from other causes, may be suggested in severe HSE, with several good results reported in the literature.

Mots clés

Decompressive craniectomy, Encephalitis, Herpes, Intracranial pressure, Simplex virus

Référence

Neurochirurgie. 2018 06;64(3):183-189