Leukocyte cell population data in patients with cardiac surgery and cardiopulmonary bypass: A potential readily available tool to monitor immunity.
Fiche publication
Date publication
janvier 2023
Journal
Frontiers in immunology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MASSON David
Tous les auteurs :
Nguyen M, Stiel L, Guilloteau A, Bahr PA, Masson D, Thomas C, Blot M, Guy J, Fontaine C, Durand B, Bouhemad B, Guinot PG
Lien Pubmed
Résumé
Cardiac surgery with cardiopulmonary bypass triggers sterile inflammation that is responsible for post-operative morbidity. Automated flow cytometry devices used for leucocyte count provide cell population data (CPD) regarding fluorescence intensity, size and granularity of leukocytes that have never been studied in the context of sterile inflammation. Our objective was to explore leukocyte cell population data in patients undergoing cardiac surgery with cardiopulmonary bypass in order to determine whether CPD could be used to monitor immune cell activation.
Mots clés
acute kidney injury, biomarker, cardiac surgery, cardiopulmonary bypass, cell population data, immunity, inflammation, post-operative outcome
Référence
Front Immunol. 2023 01 19;13:1101937