Treatment of dissecting cellulitis of the scalp with tumor necrosis factor inhibitors: a retrospective multicenter study.
Fiche publication
Date publication
janvier 2023
Journal
Clinical and experimental dermatology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr AUBIN François
Tous les auteurs :
Alzahrani M, Coste V, Konstantinou MP, Reguiai Z, Villani A, Hotz C, Viguier M, Pruvost-Balland C, Dupuy A, Wolkenstein P, Brun A, Aubin F, Gallais Sérézal I,
Lien Pubmed
Résumé
Although retinoids are considered as the most effective treatment, management of dissecting cellulitis of the scalp (DCS) is often challenging. A multicenter retrospective study was conducted to evaluate the efficacy of anti-TNF agents in treating DCS after failure of other conventional treatments. Twenty-six patients were included. After a mean treatment duration of 19 ± 21 months, the mean PGA score decreased by 56% as the number of abscesses (-89%), the number of inflammatory nodules (-70%), the mean NRS score for pain severity (-68%) and the mean DLQI (-29%). This study confirms the efficacy of anti-TNF agents in treating DCS patients resistant to conventional therapies.
Référence
Clin Exp Dermatol. 2023 01 26;: