A multi-omic analysis reveals the esophageal dysbiosis as the predominant trait of eosinophilic esophagitis.
Fiche publication
Date publication
janvier 2023
Journal
Journal of translational medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Massimino L, Barchi A, Mandarino FV, Spanò S, Lamparelli LA, Vespa E, Passaretti S, Peyrin-Biroulet L, Savarino EV, Jairath V, Ungaro F, Danese S
Lien Pubmed
Résumé
Eosinophilic esophagitis (EoE) is a chronic immune-mediated rare disease, characterized by esophageal dysfunctions. It is likely to be primarily activated by food antigens and is classified as a chronic disease for most patients. Therefore, a deeper understanding of the pathogenetic mechanisms underlying EoE is needed to implement and improve therapeutic lines of intervention and ameliorate overall patient wellness.
Mots clés
Esophagus, Microbiota, Transcriptomics, Web app
Référence
J Transl Med. 2023 01 25;21(1):46