Preclinical safety study of nacre powder in an intraosseous sheep model.
Fiche publication
Date publication
septembre 2022
Journal
BMJ open science
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MAINARD Didier
Tous les auteurs :
Iandolo D, Laroche N, Nguyen DK, Normand M, Met C, Zhang G, Vico L, Mainard D, Rousseau M
Lien Pubmed
Résumé
The purpose of this preclinical study was to evaluate the safety, the local tissue effects and bone healing performance (osteoconduction, osseointegration) of nacre powder in a sheep intraosseous implantation model. This represents the first preclinical study to assess nacre safety and efficacy in supporting new bone formation in accordance with the ISO 10993 standard for biomedical devices.
Mots clés
Biomedical Research, Models, Animal, Sheep
Référence
BMJ Open Sci. 2022 09 15;6(1):e100231