SCAVENGER RECEPTOR CLASS B TYPE I GENETIC VARIANTS ASSOCIATED WITH DISEASE SEVERITY IN CHRONIC HEPATITIS C VIRUS INFECTION.
Fiche publication
Date publication
novembre 2022
Journal
Journal of medical virology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BAUMERT Thomas
Tous les auteurs :
Arandhara VL, Patrick McClure C, Tarr AW, Chappell S, Morgan K, Baumert TF, Irving WL, Ball JK
Lien Pubmed
Résumé
Analysis of host genetic polymorphisms is an increasingly important tool for understanding and predicting pathogenesis and treatment response of viral diseases. The gene locus of scavenger receptor class B type I (SR-BI), encoding a cell entry factor and receptor for hepatitis C virus (HCV), contains several genetic polymorphisms.
Mots clés
HCV, SR-BI, liver disease, rs5888, scavenger receptor class B type 1, single nucleotide polymorphisms
Référence
J Med Virol. 2022 11 22;: