The appendix orchestrates T-cell mediated immunosurveillance in colitis-associated cancer.
Fiche publication
Date publication
novembre 2022
Journal
Cellular and molecular gastroenterology and hepatology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FREUND Jean-Noël
Tous les auteurs :
Collard MK, Tourneur-Marsille J, Uzzan M, Albuquerque M, Roy M, Dumay A, Freund JN, Hugot JP, Guedj N, Treton X, Panis Y, Ogier-Denis E
Lien Pubmed
Résumé
While appendectomy may reduce colorectal inflammation in patients with ulcerative colitis (UC), this surgical procedure has been suggested to be associated with an increased risk of colitis-associated cancer (CAC). Our aim was to explore the mechanism underlying the appendectomy-associated increased risk of CAC.
Mots clés
Appendectomy, Appendicitis, Inflammatory Bowel Disease, Ulcerative Colitis
Référence
Cell Mol Gastroenterol Hepatol. 2022 11 1;: