Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas.
Fiche publication
Date publication
juin 2020
Journal
Progress in neuro-psychopharmacology & biological psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LUTZ Pierre-Eric
Tous les auteurs :
Jollant F, Perreira F, Fiori LM, Richard-Devantoy S, Lutz PE, Belzeaux R, Turecki G
Lien Pubmed
Résumé
Psychological pain increases the risk of suicidal ideas and acts, and represents a potential therapeutic target. However, the mechanisms of mental pain remain unclear. Here, we assessed the peripheral transcriptomic and central neural correlates of mental pain during a depressive episode.
Mots clés
Neuroimaging, Nociceptin, Psychological pain, Serotonin, Transcriptomics
Référence
Prog Neuropsychopharmacol Biol Psychiatry. 2020 06 8;100:109909