Spectrum Effect and Spectrum Bias in the Screening Test Performance for Amnestic Mild Cognitive Impairment: What are the Clinical Implications?

Fiche publication


Date publication

janvier 2015

Journal

Journal of Alzheimer's disease : JAD

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MAUNY Frédéric


Tous les auteurs :
Chopard G, Puyraveau M, Binetruy M, Meyer A, Vandel P, Magnin E, Berger E, Galmiche J, Mauny F

Résumé

A single cutoff is widely used to screen amnestic mild cognitive impairment (aMCI). However, results of screening test performance are never adjusted for spectrum effect and spectrum bias.

Mots clés

Age Factors, Aged, Aged, 80 and over, Bias, Cognitive Dysfunction, diagnosis, Educational Status, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Sensitivity and Specificity

Référence

J. Alzheimers Dis.. 2015 ;48(2):385-93