Nanostructured Capsules for Cartilage Tissue Engineering.
Fiche publication
Date publication
janvier 2015
Journal
Methods in molecular biology (Clifton, N.J.)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MANO João F.
Tous les auteurs :
Correia CR, Reis RL, Mano JF
Lien Pubmed
Résumé
Polymeric multilayered capsules (PMCs) have found great applicability in bioencapsulation, an evolving branch of tissue engineering and regenerative medicine. Here, we describe the production of hierarchical PMCs composed by an external multilayered membrane by layer-by-layer assembly of poly(L-lysine), alginate, and chitosan. The core of the PMCs is liquified and encapsulates human adipose stem cells and surface-functionalized collagen II-TGF-β3 poly(L-lactic acid) microparticles for cartilage tissue engineering.
Mots clés
Bioencapsulation, Capsules, Cartilage regeneration, Collagen II, Layer-by-layer, Microparticles, Stem cells, TGF-β3, Tissue engineering
Référence
Methods Mol. Biol.. 2015 ;1340:181-9