Micro-/nano-structured superhydrophobic surfaces in the biomedical field: part I: basic concepts and biomimetic approaches.

Fiche publication


Date publication

janvier 2015

Journal

Nanomedicine (London, England)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MANO João F.


Tous les auteurs :
Lima AC, Mano JF

Résumé

Inspired by natural structures, great attention has been devoted to the study and development of surfaces with extreme wettable properties. The meticulous study of natural systems revealed that the micro/nano-topography of the surface is critical to obtaining unique wettability features, including superhydrophobicity. However, the surface chemistry also has an important role in such surface characteristics. As the interaction of biomaterials with the biological milieu occurs at the surface of the materials, it is expected that synthetic substrates with extreme and controllable wettability ranging from superhydrophilic to superhydrophobic regimes could bring about the possibility of new investigations of cell-material interactions on nonconventional surfaces and the development of alternative devices with biomedical utility. This first part of the review will describe in detail how proteins and cells interact with micro/nano-structured surfaces exhibiting extreme wettabilities.

Mots clés

bioinspired, biomimetic, cell adhesion, cell proliferation, contact angles, micro/nano-roughness, nature, protein adsorption, superhydrophilic, superhydrophobic, surfaces, tissue engineering, wettability

Référence

Nanomedicine (Lond). 2015 Jan;10(1):103-19