Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics.
Fiche publication
Date publication
janvier 2015
Journal
Current pharmaceutical design
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DUVAL Raphaël
Tous les auteurs :
Diab R, Khameneh B, Joubert O, Duval R
Lien Pubmed
Résumé
Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over "naked" ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.
Mots clés
Animals, Anti-Bacterial Agents, administration & dosage, Bacteria, drug effects, Bacterial Infections, drug therapy, Drug Delivery Systems, Drug Resistance, Bacterial, Humans, Nanoparticles, Nanotechnology
Référence
Curr. Pharm. Des.. 2015 ;21(28):4095-105