In vitro and in vivo evaluation of the inflammatory potential of various nanoporous hydroxyapatite biomaterials.
Fiche publication
Date publication
janvier 2015
Journal
Nanomedicine (London, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ANSELME Karine, Pr LAQUERRIERE Patrice, Dr VELARD Frédéric
Tous les auteurs :
Velard F, Schlaubitz S, Fricain JC, Guillaume C, Laurent-Maquin D, Möller-Siegert J, Vidal L, Jallot E, Sayen S, Raissle O, Nedelec JM, Vix-Guterl C, Anselme K, Amédée J, Laquerrière P
Lien Pubmed
Résumé
To discriminate the most important physicochemical parameters for bone reconstruction, the inflammatory potential of seven nanoporous hydroxyapatite powders synthesized by hard or soft templating was evaluated both in vitro and in vivo.
Mots clés
Animals, Biocompatible Materials, chemistry, Bone Substitutes, chemistry, Cells, Cultured, Durapatite, toxicity, Female, Humans, In Vitro Techniques, Inflammation, chemically induced, Inflammation Mediators, metabolism, Materials Testing, Mice, Mice, Inbred BALB C, Nanomedicine, Nanopores, Osseointegration, Powders
Référence
Nanomedicine (Lond). 2015 ;10(5):785-802