Fatty acid profiles in demented patients: identification of hexacosanoic acid (C26:0) as a blood lipid biomarker of dementia.
Fiche publication
Date publication
janvier 2015
Journal
Journal of Alzheimer's disease : JAD
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LIZARD Gérard
Tous les auteurs :
Zarrouk A, Riedinger JM, Ahmed SH, Hammami S, Chaabane W, Debbabi M, Ben Ammou S, Rouaud O, Frih M, Lizard G, Hammami M
Lien Pubmed
Résumé
Several lipid metabolism alterations have been described in the brain and plasma of Alzheimer's disease (AD) patients, suggesting a relation between lipid metabolism alteration and dementia.
Mots clés
Aged, Aged, 80 and over, Chromatography, Gas, Dementia, blood, Erythrocytes, pathology, Fatty Acids, blood, Female, Humans, Male, Mass Spectrometry, Mental Status Schedule, Middle Aged, Neuropsychological Tests, ROC Curve
Référence
J. Alzheimers Dis.. 2015 ;44(4):1349-59