Central venous thrombosis and thrombophilia in cystic fibrosis: A prospective study.
Fiche publication
Date publication
janvier 2015
Journal
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HUET Frédéric
Tous les auteurs :
Munck A, Kheniche A, Alberti C, Hubert D, Martine RG, Nove-Josserand R, Pin I, Bremont F, Chiron R, Couderc L, Dalphin ML, Darviot E, Delaisi B, Dominique S, Durieu I, Fanton A, Fayon M, Gérardin M, Giniès JL, Giraut C, Grenet D, Guillot M, Huet F, Le Bourgeois M, Murris-Epin M, Ramel S, Sardet A, Sermet-Gaudelus I, Varaigne F, Wanin S, Weiss L, Hurtaud MF
Lien Pubmed
Résumé
Catheter venous thrombosis may result in life-threatening embolic complications. Recently, a thrombophilic tendency was described in cystic fibrosis (CF), the significance of which remains unclear. The aims of this study were to (1) document the frequency of catheter venous thrombosis detected by colour-Doppler-ultrasound (Doppler-US), (2) assess genetic and acquired thrombophilia risk factors for catheter venous thrombosis and hypercoagulability status and (3) provide recommendations on laboratory screening when considering insertion of a totally implantable vascular access device (TIVAD) in CF patients.
Mots clés
Adolescent, Adult, Age Distribution, Catheters, Indwelling, adverse effects, Child, Cohort Studies, Comorbidity, Cystic Fibrosis, diagnosis, Female, Humans, Male, Prevalence, Prognosis, Prospective Studies, Severity of Illness Index, Sex Distribution, Thrombophilia, blood, Ultrasonography, Doppler, methods, Venous Thrombosis, diagnostic imaging, Young Adult
Référence
J. Cyst. Fibros.. 2015 Jan;14(1):97-103