Identification of bacterial lipopeptides as key players in IBS.
Fiche publication
Date publication
octobre 2022
Journal
Gut
Auteurs
Membres identifiés du Cancéropôle Est :
Pr POISBEAU Pierrick
Tous les auteurs :
Petitfils C, Maurel S, Payros G, Hueber A, Agaiz B, Gazzo G, Marrocco R, Auvray F, Langevin G, Motta JP, Floch P, Tremblay-Franco M, Galano JM, Guy A, Durand T, Lachambre S, Durbec A, Hussein H, Decraecker L, Bertrand-Michel J, Saoudi A, Oswald E, Poisbeau P, Dietrich G, Melchior C, Boeckxstaens G, Serino M, Le Faouder P, Cenac N
Lien Pubmed
Résumé
Clinical studies revealed that early-life adverse events contribute to the development of IBS in adulthood. The aim of our study was to investigate the relationship between prenatal stress (PS), gut microbiota and visceral hypersensitivity with a focus on bacterial lipopeptides containing γ-aminobutyric acid (GABA).
Mots clés
ENTERIC BACTERIAL MICROFLORA, IRRITABLE BOWEL SYNDROME, LACTIC ACID BACTERIA, LIPIDS, VISCERAL HYPERSENSITIVITY
Référence
Gut. 2022 10 14;: