Genetic studies in isolated bilateral clubfoot detected by prenatal ultrasound.
Fiche publication
Date publication
septembre 2022
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BONNET Céline
Tous les auteurs :
Dap M, Harter H, Lambert L, Perdriolle-Galet E, Bonnet C, Morel O
Lien Pubmed
Résumé
To evaluate the contribution of genetic investigations in case of isolated bilateral clubfoot detected by routine prenatal ultrasound. Pathogenic Copy Number Variations is about 3.9% in fetuses with isolated clubfoot (uni- or bilateral). We hypothesize that this rate could be higher in a homogenous group of fetuses with bilateral clubfoot.
Mots clés
Clubfoot, bilateral clubfoot, chromosomal microarray analysis, genetic, prenatal diagnosis, ultrasound
Référence
J Matern Fetal Neonatal Med. 2022 09 27;:1-4