Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers.
Fiche publication
Date publication
août 2022
Journal
Polymers
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRASSART-PASCO Sylvie
Tous les auteurs :
Bacha K, Estager J, Brassart-Pasco S, Chemotti C, Fernandes AE, Mbakidi JP, Deleu M, Bouquillon S
Lien Pubmed
Résumé
For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells.
Mots clés
antioxidant, dendrimers, flow chemistry, microwave, phenolic acids
Référence
Polymers (Basel). 2022 08 27;14(17):