[Embryo stage impact on the risk of ectopic pregnancy after In Vitro Fecondation].
Fiche publication
Date publication
août 2022
Journal
Gynecologie, obstetrique, fertilite & senologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROUX Christophe
Tous les auteurs :
Caroff A, Roux C, Pretalli JB, Nallet C
Lien Pubmed
Résumé
Objectives : Ectopic pregnancies are still the first mortality cause of the first semestre of pregnancy. They are much more frequent in IVF (2-5%) than in the standard population (1-2%). The aim of this study was to compare the rate of ectopic pregnancies following a fresh embryo transfer done whether at an clived embryo stage (day 2 or 3 of the embryo development) or at a blastocyst stage (day 5 or 6 of the embryo development). Methods : This is a monocentric retrospective study including all 18 to 43 year-old patients getting pregnant (ßHCG > 100 UI/L) after a fresh embryo transfer from In Vitro Fecondation with or without Intra-Cytoplasmic Sperm Injection, between January 1st 2014 and December 30th 2020 in the Hospital of Besançon (France). This population has been divided into 2 groups according to the embryo stage on the day of transfer. Results : Nine hundred and twenty two patients have been included. There were statistically more ectopic pregnancies after a blastocyst transfer (n= 4 ; 5,4%) than after a clived embryo transfer (n=14 ; 1,7%). (p=0,049) Conclusion : In our population, there were more ectopic pregnancies from blastocyst transfers than from clived embryoes.
Mots clés
assistance médicale à la procreation, assisted procreation, blastocyst, blastocyste, clived embryo, ectopic pregnancy, embryon clivé, fresh embryo transfer, fécondation in vitro, grossesse extra-utérine, in vitro fecundation, transfert d’embryon frais
Référence
Gynecol Obstet Fertil Senol. 2022 08 30;: