Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype.
Fiche publication
Date publication
mars 2015
Journal
Journal of neuroinflammation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DE SEZE Jérôme
Tous les auteurs :
Pröbstel AK, Rudolf G, Dornmair K, Collongues N, Chanson JB, Sanderson NS, Lindberg RL, Kappos L, de Seze J, Derfuss T
Lien Pubmed
Résumé
Antibodies against myelin oligodendrocyte glycoprotein (MOG) have been identified in a subgroup of pediatric patients with inflammatory demyelinating disease of the central nervous system (CNS) and in some patients with neuromyelitis optica spectrum disorder (NMOSD). The aim of this study was to examine the frequency, clinical features, and long-term disease course of patients with anti-MOG antibodies in a European cohort of NMO/NMOSD.
Mots clés
Adult, Aged, Aquaporin 4, immunology, Autoantibodies, blood, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Multiple Sclerosis, Relapsing-Remitting, blood, Myelin-Oligodendrocyte Glycoprotein, immunology, Neuromyelitis Optica, blood, Retrospective Studies, Young Adult
Référence
J Neuroinflammation. 2015 Mar 8;12:46