Effect of chronic left ventricular unloading on myocardial remodeling: Multimodal assessment of two heterotopic heart transplantation techniques.
Fiche publication
Date publication
avril 2015
Journal
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARIE Pierre-Yves, Pr GAUCHOTTE Guillaume
Tous les auteurs :
Liu Y, Maureira P, Gauchotte G, Falanga A, Marie V, Olivier A, Groubatch F, Gu C, Marie PY, Tran N
Lien Pubmed
Résumé
Cardiac recovery is possible by means of mechanical unloading yet remains rare. Excessive unloading-associated myocardial atrophy and fibrosis may adversely affect the process of reverse remodeling. In this study, we sought to evaluate the effect of different intensities of chronic left ventricular (LV) unloading on myocardial remodeling.
Mots clés
Animals, Chronic Disease, Disease Models, Animal, Heart Transplantation, Male, Rats, Rats, Inbred Lew, Transplantation, Heterotopic, Ventricular Dysfunction, Left, physiopathology, Ventricular Remodeling
Référence
J. Heart Lung Transplant.. 2015 Apr;34(4):594-603