[Stereotactic body radiation therapy for spinal metastases].
Fiche publication
Date publication
octobre 2016
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FAIVRE Jean-Christophe
Tous les auteurs :
Pasquier D, Martinage G, Mirabel X, Lacornerie T, Makhloufi S, Faivre JC, Thureau S, Lartigau É
Lien Pubmed
Résumé
After the liver and lungs, bones are the third most common sites of cancer metastasis. Palliative radiotherapy for secondary bone tumours helps relieve pain, improve the quality of life and reduce the risk of fractures. Stereotactic body radiotherapy can deliver high radiation doses with very tight margins, which has significant advantages when treating tumours close to the spinal cord. Strict quality control is essential as dose gradient at the edge of the spinal cord is important. Optimal schedule is not defined. A range of dose-fractionation schedules have been used. Pain relief and local control are seen in over 80%. Toxicity rates are low, although vertebral fracture may occur. Ongoing prospective studies will help clarify its role in the management of oligometastatic patients.
Mots clés
Hypofractionation, Hypofractionnement, Métastases vertébrales, Oligometastasis, Oligométastases, Radiothérapie stéréotaxique, Spinal metastases, Stereotactic radiotherapy
Référence
Cancer Radiother. 2016 Oct;20(6-7):500-7