Effects of Steroidal Mineralocorticoid Receptor Antagonists on Acute and Chronic Estimated Glomerular Filtration Rate Slopes in Patients with Chronic Heart Failure.
Fiche publication
Date publication
juillet 2022
Journal
European journal of heart failure
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Vaduganathan M, Ferreira JP, Rossignol P, Neuen B, Claggett BL, Pfeffer MA, McMurray JJV, Pitt B, Zannad F, Solomon SD
Lien Pubmed
Résumé
Steroidal mineralocorticoid receptor antagonists (MRAs) form a cornerstone of the management of heart failure (HF), but little is known about the long-term effects of MRA therapy on kidney function. We evaluated acute and chronic estimated glomerular function (eGFR) slopes in the 2 largest completed trials testing steroidal MRAs in chronic HF.
Référence
Eur J Heart Fail. 2022 07 22;: