Bio-sourced phosphoprotein-based synthesis of silver-doped macroporous zinc phosphates and their antibacterial properties.
Fiche publication
Date publication
juillet 2018
Journal
RSC advances
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ANSELME Karine
Tous les auteurs :
Hinostroza Ramos JV, Anselme K, Simon-Masseron A, Ploux L
Lien Pubmed
Résumé
The usual sources of phosphorus for metal phosphates are obtained from phosphate rocks, of which resources are depleted. As a substitute for these mineral sources, an original method of synthesis has been developed to prepare macroporous zinc phosphates using casein phosphoprotein. This bio-sourced reactant plays during the synthesis the roles of both a phosphorus source and a reducing agent for silver nanoparticles. Thus, zinc phosphates loaded with different Ag contents (up to 6.4 wt%) are prepared hydrothermal treatment at 100 °C. Silver nanoparticles co-crystallized with hopeite, Zn(PO) and/or ZnPO. In addition, casein induces porosity within the zinc phosphate framework and provides macropores (diameter of >50 nm) during calcination. The antibacterial properties against K12 bacteria of Ag-containing and Ag-free porous zinc phosphates (calcined at 750 °C) were also tested for the first time.
Référence
RSC Adv. 2018 Jul 9;8(44):25112-25122