Cost and Toxicity Comparisons of Two IMRT Techniques for Prostate Cancer: A Micro-Costing Study and Weighted Propensity Score Analysis Based on a Prospective Study.

Fiche publication


Date publication

janvier 2021

Journal

Frontiers in oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr NOEL Georges, Pr PEIFFERT Didier


Tous les auteurs :
Masson I, Bellanger M, Perrocheau G, Mahé MA, Azria D, Pommier P, Mesgouez-Nebout N, Giraud P, Peiffert D, Chauvet B, Dudouet P, Salem N, Noël G, Khalifa J, Latorzeff I, Guérin-Charbonnel C, Supiot S

Résumé

Intensity modulated radiation therapy (IMRT) combined with androgen deprivation therapy (ADT) has become the standard treatment for patients with high-risk prostate cancer. Two techniques of rotational IMRT are commonly used in this indication: Volumetric Modulated Arc Therapy (VMAT) and helical tomotherapy (HT). To the best of our knowledge, no study has compared their related costs and clinical effectiveness and/or toxicity in prostate cancer. We aimed to assess differences in costs and toxicity between VMAT and HT in patients with high-risk prostate cancer with pelvic irradiation.

Mots clés

France, Volumetric Arc Therapy (VMAT), helical tomotherapy (HT), high risk prostate cancers, inverse probability of treatment weighting (IPTW), micro-costing, toxicity

Référence

Front Oncol. 2021 ;11:781121