Genomics of Clear-cell Renal Cell Carcinoma: A Systematic Review and Meta-analysis.
Fiche publication
Date publication
janvier 2022
Journal
European urology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr FEUGEAS Jean-Paul
Tous les auteurs :
Bui TO, Dao VT, Nguyen VT, Feugeas JP, Pamoukdjian F, Bousquet G
Lien Pubmed
Résumé
Although antiangiogenic treatments and immunotherapies have significantly improved the prognosis of metastatic renal cell carcinoma (RCC), many patients will develop resistance, leading to treatment failure. Genetic tumor heterogeneity is a major cause of this resistance.
Mots clés
Genomics, Metastases, Mutation, Primary tumor, Renal cell carcinoma
Référence
Eur Urol. 2022 Jan 3;: