Genetic Alterations in Mitochondrial DNA Are Complementary to Nuclear DNA Mutations in Pheochromocytomas.
Fiche publication
Date publication
janvier 2022
Journal
Cancers
Auteurs
Membres identifiés du Cancéropôle Est :
Mme LOMAZZI Sandra
Tous les auteurs :
Tabebi M, Łysiak M, Dutta RK, Lomazzi S, Turkina MV, Brunaud L, Gimm O, Söderkvist P
Lien Pubmed
Résumé
Somatic mutations, copy-number variations, and genome instability of mitochondrial DNA (mtDNA) have been reported in different types of cancers and are suggested to play important roles in cancer development and metastasis. However, there is scarce information about pheochromocytomas and paragangliomas (PCCs/PGLs) formation.
Mots clés
genetic alterations, mitochondrial DNA, pheochromocytomas and paragangliomas
Référence
Cancers (Basel). 2022 Jan 6;14(2):