Nanomedicine and Periodontal Regenerative Treatment.
Fiche publication
Date publication
janvier 2022
Journal
Dental clinics of North America
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BENKIRANE-JESSEL Nadia
Tous les auteurs :
Huck O, Stutz C, Gegout PY, Özçelik H, Benkirane-Jessel N, Petit C, Batool F
Lien Pubmed
Résumé
Current periodontal treatments aim to control bacterial infection and decrease inflammation. To optimize contemporary conventional treatments that present limitations owing to an inability to reach the lesion site, new methods are based on nanomedicine. Nanomedecine allows delivery of host-modulatory drugs or antibacterial molecules at the lesion site in an optimal concentration with decreased toxicity and risk of systemic side effects. Chitosan and polylactic-co-glycolic acid-loaded nanoparticles, carbon quantum dots, and mesoporous silicates open new perspectives in periodontitis management. The potential therapeutic impact of the main nanocarriers is discussed.
Mots clés
Biomaterials, Inflammation, Nanocarriers, Nanomedicine, Periodontitis
Référence
Dent Clin North Am. 2022 Jan;66(1):131-155