LRP-1 Matricellular Receptor Involvement in Triple Negative Breast Cancer Tumor Angiogenesis.
Fiche publication
Date publication
octobre 2021
Journal
Biomedicines
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DEDIEU Stéphane, Dr DEVY Jérôme, Dr ETIQUE Nicolas, Dr THEVENARD-DEVY Jessica, Dr BOULAGNON-ROMBI Camille, Dr SCHNEIDER Christophe
Tous les auteurs :
Campion O, Thevenard Devy J, Billottet C, Schneider C, Etique N, Dupuy JW, Raymond AA, Boulagnon Rombi C, Meunier M, Djermoune EH, Lelièvre E, Wahart A, Bour C, Hachet C, Cairo S, Bikfalvi A, Dedieu S, Devy J
Lien Pubmed
Résumé
LRP-1 is a multifunctional scavenger receptor belonging to the LDLR family. Due to its capacity to control pericellular levels of various growth factors and proteases, LRP-1 plays a crucial role in membrane proteome dynamics, which appears decisive for tumor progression.
Mots clés
LRP-1, TNBC, angiogenesis, breast cancer
Référence
Biomedicines. 2021 Oct 9;9(10):