Comparison of two techniques (in vivo and ex-vivo) for evaluating the elastic properties of the ascending aorta: Prospective cohort study.
Fiche publication
Date publication
janvier 2021
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Pr COCHET Alexandre
Tous les auteurs :
Morgant MC, Lin S, Marin-Castrillon D, Bernard C, Laubriet A, Cochet A, Lalande A, Bouchot O
Lien Pubmed
Résumé
Aneurysms of the ascending aorta (AA) correspond to a dilatation of the ascending aorta that progressively evolves over several years. The main complication of aneurysms of the ascending aorta is type A aortic dissection, which is associated with very high rates of morbidity and mortality. Prophylactic ascending aorta replacement guidelines are currently based on maximal AA diameter. However, this criterion is imperfect. Stretching tests on the aorta carried out ex-vivo make it possible to determine the elastic properties of healthy and aneurysmal aortic fragments (tension test, resistance before rupture). For several years now, cardiac magnetic resonance imaging (MRI) has provided another means of evaluating the elastic properties of the aorta. This imaging technique has the advantage of being non-invasive and of establishing aortic compliance (local measurement of stiffness) without using contrast material by measuring the variation of the aortic surface area during the cardiac cycle, and pulse wave velocity (overall stiffness of the aorta).
Référence
PLoS One. 2021 ;16(9):e0256278