Innovative procedure for measuring left ventricular ejection fraction from F-FDG first-pass ultra-sensitive digital PET/CT images: evaluation with an anthropomorphic heart phantom.

Fiche publication


Date publication

mai 2021

Journal

EJNMMI physics

Auteurs

Membres identifiés du Cancéropôle Est :
Dr RETIF Paul


Tous les auteurs :
Verrecchia-Ramos E, Morel O, Retif P, Ben Mahmoud S

Résumé

Left ventricular ejection fraction (LVEF) is usually measured by cine-cardiac magnetic resonance imaging (MRI), planar and single-photon emission-computerized tomography (SPECT) equilibrium radionuclide angiocardiography (ERNA), and echocardiography. It would be clinically useful to measure LVEF from first-pass positron-emission tomography/computed tomography (PET/CT) radionuclide angiography, but this approach has been limited by fast radiotracer diffusion. Ultra-sensitive digital PET systems can produce high-quality images within 3-s acquisition times. This study determined whether digital PET/CT accurately measured LVEF in an anthropomorphic heart phantom under conditions mimicking radiotracer first-pass into the cardiac cavities.

Mots clés

Digital PET/CT, First-pass, Heart phantom, LVEF, “Pseudo-planar” PET

Référence

EJNMMI Phys. 2021 May 20;8(1):42