A case report of blastic plasmacytoid dendritic cell neoplasm in a hispanic child.
Fiche publication
Date publication
janvier 2021
Journal
Leukemia research reports
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DECONINCK Eric
Tous les auteurs :
Tanchiva KO, Chavez PC, Guevara SLL, Vicuña CRQ, Bhardwaj N, Lansigan F, Deconinck E
Lien Pubmed
Résumé
Plasmacytoid dendritic cell neoplasms are aggressive and rare hematologic malignancies characterized by clonal expansion of plasmacytoid dendritic cells with frequent cutaneous involvement. The pathogenesis is not well established, and it shows enhanced expression of CD56, CD4 and CD123 detected by flow cytometry and immunohistochemistry. We report a case report of this rare disease in a hispanic child with complete remission after using a protocol for high-risk acute lymphoblastic leukemia.
Mots clés
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), Case report, Pediatric
Référence
Leuk Res Rep. 2021 ;16:100262