Cytokines as new biomarkers of skin wound vitality.
Fiche publication
Date publication
juillet 2021
Journal
International journal of legal medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GAUCHOTTE Guillaume
Tous les auteurs :
Peyron PA, Colomb S, Becas D, Adriansen A, Gauchotte G, Tiers L, Marin G, Lehmann S, Baccino E, Delaby C, Hirtz C
Lien Pubmed
Résumé
The diagnosis of skin wound vitality is currently based on standard histology, but histological findings lack sensitivity in case of a short survival time. New reliable biomarkers of vitality are therefore strongly needed. We assessed the ability of 10 candidate cytokines (IFN-γ, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, TNF-α) to discriminate between vital and early post-mortem wounds.
Mots clés
Cytokines, Forensic pathology, Immunoassay, Immunohistochemistry, Vitality, Wound
Référence
Int J Legal Med. 2021 Jul 27;: