Multimodal imaging as optical biopsy system for gastritis diagnosis in humans, and input of the mouse model.
Fiche publication
Date publication
juillet 2021
Journal
EBioMedicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARZANI Franck
Tous les auteurs :
Bazin T, Krebs A, Jobart-Malfait A, Camilo V, Michel V, Benezeth Y, Marzani F, Touati E, Lamarque D
Lien Pubmed
Résumé
Gastric inflammation is a major risk factor for gastric cancer. Current endoscopic methods are not able to efficiently detect and characterize gastric inflammation, leading to a sub-optimal patients' care. New non-invasive methods are needed. Reflectance mucosal light analysis is of particular interest in this context. The aim of our study was to analyze reflectance light and specific autofluorescence signals, both in humans and in a mouse model of gastritis.
Mots clés
Autofluorescence, Gastric cancer, Gastritis, Helicobacter pylori, Optical biopsy, Reflectance
Référence
EBioMedicine. 2021 Jul 2;69:103462