Influence of gender on cytokine induced depression and treatment: Gender aspects of IFN-α-induced depression.
Fiche publication
Date publication
juin 2021
Journal
Journal of affective disorders
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BAUMERT Thomas
Tous les auteurs :
Sarkar S, Kemper J, Sarkar R, Brants L, Friebe A, Spengler U, Schläpfer T, Reimer J, Buggisch P, Ockenga J, Link R, Rentrop M, Weidenbach H, Fromm G, Lieb K, Baumert TF, Discher T, Zeuzem S, Berg T, Schaefer M
Lien Pubmed
Résumé
Cytokine treatment with Interferon-alpha (IFN-α) represents a clinical model of immune associated depression, but it remains unclear if it is of the same entity as major depressive disorder (MDD). The study focuses on possible gender differences in IFN-α induced depression and effects of a pre-emptive antidepressant treatment.
Mots clés
Antidepressant therapy, Cytokine treatment, Depression, Gender, Inflammation, Interferon-alpha
Référence
J Affect Disord. 2021 Jun 23;292:766-772