Clinical significance of anti-Ro52 (TRIM21) antibodies in adult patients with connective tissue diseases.

Fiche publication


Date publication

mai 2021

Journal

European journal of internal medicine

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BONNOTTE Bernard, Pr DE CARVALHO BITTENCOURT Marcelo


Tous les auteurs :
Decker P, Moulinet T, Lopez B, Dubucquoi S, Bonnotte B, Lakomy D, Revuz S, Luc A, Bittencourt MC, Hachulla E, Jaussaud R

Résumé

Clinical significance of anti-Ro52 antibodies in connective tissue diseases (CTD) is controversial. Anti-Ro52 antibodies might be associated with a more severe CTD phenotype, especially interstitial lung disease (ILD). The aims of this study were to evaluate ILD prevalence and severity, the prevalence of micro- or macroangiopathy and CTD-associated cancers in CTD with anti-Ro52 antibodies.

Mots clés

Anti-Ro52 antibodies, Connective tissue disease, Interstitial lung disease

Référence

Eur J Intern Med. 2021 May 7;: