Breast cancer patients treated with intrathecal therapy for leptomeningeal metastases in a large real-life database.

Fiche publication


Date publication

mai 2021

Journal

ESMO open

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PETIT Thierry, Dr FUMET Jean-David, Dr JOUANNAUD Christelle


Tous les auteurs :
Carausu M, Carton M, Darlix A, Pasquier D, Leheurteur M, Debled M, Mouret-Reynier MA, Goncalves A, Dalenc F, Verret B, Campone M, Augereau P, Ferrero JM, Levy C, Fumet JD, Lefeuvre-Plesse C, Petit T, Uwer L, Jouannaud C, Larrouquere L, Chevrot M, Courtinard C, Cabel L

Résumé

Leptomeningeal metastasis (LM) is a rare complication of metastatic breast cancer (MBC), with high morbidity/mortality rates. Our study aimed to describe the largest-to-date real-life population of MBC patients treated with intrathecal (IT) therapy and to evaluate prognostic models.

Mots clés

breast cancer, cohort study, intrathecal therapy, leptomeningeal metastasis

Référence

ESMO Open. 2021 May 10;6(3):100150