Stress-first protocol for myocardial perfusion SPECT imaging with semiconductor cameras: high diagnostic performances with significant reduction in patient radiation doses.
Fiche publication
Date publication
juin 2015
Journal
European journal of nuclear medicine and molecular imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles, Pr MARIE Pierre-Yves, Pr VERGER Antoine, Dr CLAUDIN Marine
Tous les auteurs :
Perrin M, Djaballah W, Moulin F, Claudin M, Veran N, Imbert L, Poussier S, Morel O, Besseau C, Verger A, Boutley H, Karcher G, Marie PY
Lien Pubmed
Résumé
Effective doses of 14 mSv or higher are currently being attained in patients having stress and rest myocardial perfusion imaging (MPI) single photon emission computed tomography (SPECT) performed on the same day with conventional protocols. This study aimed to assess the actual reduction in effective doses as well as diagnostic performances for MPI routinely planned with: (1) high-sensitivity cadmium zinc telluride (CZT) cameras, (2) very low injected activities and (3) a stress-first protocol where the normality of stress images may lead to avoiding rest imaging.
Mots clés
Aged, Cadmium, Coronary Angiography, instrumentation, Exercise Test, methods, Female, Humans, Male, Middle Aged, Myocardial Perfusion Imaging, instrumentation, Radiation Dosage, Radiopharmaceuticals, adverse effects, Semiconductors, Technetium Tc 99m Sestamibi, adverse effects, Tellurium, Tomography, Emission-Computed, Single-Photon, instrumentation, Zinc
Référence
Eur. J. Nucl. Med. Mol. Imaging. 2015 Jun;42(7):1004-11