Specific airway resistance in healthy young Vietnamese and Caucasian adults.

Fiche publication


Date publication

juin 2015

Journal

Respiratory physiology & neurobiology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr NGUYEN-THI Phi Linh


Tous les auteurs :
Le Tuan T, Nguyen NM, Demoulin B, Bonabel C, Nguyen-Thi PL, Ioan I, Schweitzer C, Nguyen HT, Varechova S, Marchal F

Résumé

In healthy Vietnamese children the respiratory resistance has been suggested to be similar at 110 cm height but larger at 130 cm when compared with data in Caucasians from the literature, suggesting smaller airways in older Vietnamese children (Vu et al., 2008). The hypothesis tested here is whether the difference in airway resistance remains consistent throughout growth, and if it is larger in adult Vietnamese than in Caucasians. Airway resistance and Functional Residual Capacity were measured in healthy young Caucasian and Vietnamese adults in their respective native country using identical equipment and protocols. Ninety five subjects in Vietnam (60 males) and 101 in France (41 males) were recruited. Airway resistance was significantly larger in Vietnamese than in Caucasians and in females than in males, consistent with difference in body dimensions. Specific airway resistance however was not different by ethnicity or gender. The findings do not support the hypothesis that airway size at adult age - once normalized for lung volume - differs between Vietnamese and Caucasians.

Mots clés

Adolescent, Adult, Airway Resistance, physiology, Asian Continental Ancestry Group, European Continental Ancestry Group, Female, France, Humans, Male, Multivariate Analysis, Plethysmography, Sex Characteristics, Vietnam, Young Adult

Référence

Respir Physiol Neurobiol. 2015 Jun;211:17-21