Refractory hyperaldosteronism in heart failure is associated with plasma renin activity and angiotensinogen polymorphism.
Fiche publication
Date publication
juin 2015
Journal
Journal of cardiovascular medicine (Hagerstown, Md.)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Vergaro G, Fatini C, Sticchi E, Vassalle C, Gensini G, Ripoli A, Rossignol P, Passino C, Emdin M, Abbate R
Lien Pubmed
Résumé
Refractory hyperaldosteronism is frequently observed in heart failure patients on up-to-date treatment, and holds prognostic value. Our aim was to identify which factors, either genetic or nongenetic, are associated with refractory hyperaldosteronism.
Mots clés
Aged, Angiotensinogen, genetics, Biomarkers, blood, Cardiovascular Agents, therapeutic use, Female, Follow-Up Studies, Gene Frequency, Genetic Predisposition to Disease, Heart Failure, complications, Humans, Hyperaldosteronism, blood, Male, Middle Aged, Polymorphism, Genetic, Prognosis, Prospective Studies, Renin, blood, Renin-Angiotensin System, genetics
Référence
J Cardiovasc Med (Hagerstown). 2015 Jun;16(6):416-22