Paediatric CT protocol optimisation: a design of experiments to support the modelling and optimisation process.
Fiche publication
Date publication
juillet 2015
Journal
Radiation protection dosimetry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr WOLF Didier
Tous les auteurs :
Rani K, Jahnen A, Noel A, Wolf D
Lien Pubmed
Résumé
In the last decade, several studies have emphasised the need to understand and optimise the computed tomography (CT) procedures in order to reduce the radiation dose applied to paediatric patients. To evaluate the influence of the technical parameters on the radiation dose and the image quality, a statistical model has been developed using the design of experiments (DOE) method that has been successfully used in various fields (industry, biology and finance) applied to CT procedures for the abdomen of paediatric patients. A Box-Behnken DOE was used in this study. Three mathematical models (contrast-to-noise ratio, noise and CTDI vol) depending on three factors (tube current, tube voltage and level of iterative reconstruction) were developed and validated. They will serve as a basis for the development of a CT protocol optimisation model.
Mots clés
Algorithms, Analysis of Variance, Child, Contrast Media, Humans, Models, Statistical, Multidetector Computed Tomography, methods, Pediatrics, methods, Phantoms, Imaging, Radiation Dosage, Radiation, Ionizing, Radiographic Image Interpretation, Computer-Assisted, methods, Research Design, Signal-To-Noise Ratio, Tomography Scanners, X-Ray Computed
Référence
Radiat Prot Dosimetry. 2015 Jul;165(1-4):205-9