Mandibular sterile osteitis as a manifestation of SAPHO syndrome: a literature review.

Fiche publication


Date publication

décembre 2020

Journal

Journal of the European Academy of Dermatology and Venereology : JEADV

Auteurs

Membres identifiés du Cancéropôle Est :
Pr LIPSKER Dan


Tous les auteurs :
Klein C, Lipsker D

Résumé

SAPHO syndrome (« synovitis, acne, pustulosis, hyperostosis, osteitis ») is characterised by cutaneous and osteoarticular manifestations. The latter include osteitis, synovitis and hyperostosis. They most frequently involve the anterior chest wall and the sacroiliac joints. Mandible is involved in 10% of cases and this is clinically manifested by swelling, pain or trismus. We have recently seen 2 patients who had so far undiagnosed episodes of recurrent swelling of the mandible leading to repeat bone biopsies. The presence of dermatologic findings allowed diagnosing SAPHO syndrome and providing efficient treatment.

Référence

J Eur Acad Dermatol Venereol. 2020 Dec 17;: