Nanoluminal Signaling Shapes Collective Metastasis.
Fiche publication
Date publication
novembre 2020
Journal
Trends in cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GOETZ Jacky, Dr OSMANI Naël
Tous les auteurs :
Gensbittel V, Busnelli I, Osmani N, Goetz JG
Lien Pubmed
Résumé
Clustering of tumor cells is known to grant superior metastatic efficiency compared with single cells. However, the mechanisms involved remain elusive. Reporting in Cell, Wrenn et al. describe how sealed intercellular compartments, nanolumina, are used as growth factor reservoirs within tumor cell clusters to regulate tumor cell proliferation.
Référence
Trends Cancer. 2020 Nov 28;: