Brain Perfusion Before and After Surgical Treatment of Moyamoya Disease.
Fiche publication
Date publication
mai 2017
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr POROT Clémence, Pr BOULAHDOUR Hatem
Tous les auteurs :
Drouet C, Morel O, Thines L, Porot C, Boulahdour H
Lien Pubmed
Résumé
Moyamoya disease is characterized by bilateral progressive terminal internal carotid arteries steno-occlusion. In this patient, the disease affected middle cerebral arteries and was disclosed after a left frontal cerebral infarction. Brain HMPAO perfusion scintigraphy with acetazolamide challenge, obtained before surgical treatment, demonstrates an extended bilateral frontal hypoperfusion with a vascular steal phenomenon. The same examination obtained after surgical treatment demonstrates a frank improvement in basal brain vascularization, with nearly complete correction of vascular steal phenomenon. HMPAO brain scintigraphy is a very useful tool in the assessment of moyamoya disease severity before surgery and for the evaluation of treatment efficiency.
Mots clés
Acetazolamide, Brain, diagnostic imaging, Cerebrovascular Circulation, Humans, Infarction, Middle Cerebral Artery, diagnostic imaging, Moyamoya Disease, complications, Radionuclide Imaging
Référence
Clin Nucl Med. 2017 May;42(5):e269-e272