Physically-triggered nanosystems based on two-dimensional materials for cancer theranostics.
Fiche publication
Date publication
janvier 2019
Journal
Advanced drug delivery reviews
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MENARD-MOYON Cécilia, Dr BIANCO Alberto
Tous les auteurs :
Ji DK, Ménard-Moyon C, Bianco A
Lien Pubmed
Résumé
There is an increasing demand to develop effective methods for treating malignant diseases to improve healthcare in our society. Stimuli-responsive nanosystems, which can respond to internal or external stimuli are promising in cancer therapy and diagnosis due to their functionality and versatility. As a newly emerging class of nanomaterials, two-dimensional (2D) nanomaterials have attracted huge interest in many different fields including biomedicine due to their unique physical and chemical properties. In the past decade, stimuli-responsive nanosystems based on 2D nanomaterials have been widely studied, showing promising applications in cancer therapy and diagnosis, including phototherapies, magnetic therapy, drug and gene delivery, and non-invasive imaging. Here, we will focus our attention on the state-of-the-art of physically-triggered nanosystems based on graphene and two-dimensional nanomaterials for cancer therapy and diagnosis. The physical triggers include light, temperature, magnetic and electric fields.
Mots clés
2D Materials, Diagnosis, Graphene, Nanomaterials, Theragnosis, Therapy
Référence
Adv Drug Deliv Rev. 2019 01 1;138:211-232