Bayesian predictive probabilities: a good way to monitor clinical trials.
Fiche publication
Date publication
octobre 2020
Journal
British journal of anaesthesia
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MEYER Nicolas
Tous les auteurs :
Ferreira D, Ludes PO, Diemunsch P, Noll E, Torp KD, Meyer N
Lien Pubmed
Résumé
Bayesian methods, with the predictive probability (PredP), allow multiple interim analyses with interim posterior probability (PostP) computation, without the need to correct for multiple looks at the data. The objective of this paper was to illustrate the use of PredP by simulating a sequential analysis of a clinical trial.
Mots clés
Bayesian statistics, RCT, clinical trial, monitoring, predictive probabilities, statistics
Référence
Br J Anaesth. 2020 Oct 28;: