[Vaccination against papillomavirus : arguments and evidence of effectiveness].
Fiche publication
Date publication
janvier 2020
Journal
La Revue du praticien
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PRETET Jean-Luc, Dr SELMANI Zohair
Tous les auteurs :
Prétet JL, Selmani Z, Mougin C, Pepin-Puget L, Lepiller Q
Lien Pubmed
Résumé
Vaccination against papillomavirus: arguments and evidence of effectiveness. Vaccination against human papillomavirus is a major advance in the prevention of cervical cancer. Evidence of its effectiveness has accumulated over the past thirty years since basic research has demonstrated the ability of viral pseudoparticles to induce immune responses in animals. Large human clinical trials followed to demonstrate the safety and efficacy of vaccination against targeted HPV infections and their associated lesions. After its approval and marketing the vaccine efficacy was measured at the level of entire populations, confirming its effectiveness and medical interest. Today, models predict a possible eradication of cervical cancer in the coming decades.
Mots clés
Disease Eradication, Papillomavirus Vaccines, Uterine Cervical Neoplasms
Référence
Rev Prat. 2020 Jan;70(1):99-103