Immunohistochemistry with anti-MAL antibody and RNAscope with MAL probes are complementary techniques for diagnosis of primary mediastinal large B-cell lymphoma.

Fiche publication


Date publication

août 2020

Journal

Journal of clinical pathology

Auteurs

Membres identifiés du Cancéropôle Est :
Mr MONNIEN Franck


Tous les auteurs :
Jacquier A, Syrykh C, Bedgedjian I, Monnien F, Laurent C, Valmary-Degano S, Brousset P

Résumé

Primary mediastinal large B-cell lymphoma (PMBL) diagnosis can be challenging on needle biopsies. Robust techniques are needed to ensure diagnosis of this lymphoma which is highly sensitive to recently developed therapy protocols.

Mots clés

immunohistochemistry, in situ hybridisation, lymphoma

Référence

J. Clin. Pathol.. 2020 Aug 24;: